Anti-Mouse IFNβ - Purified
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411.80 ₪
Interferons (IFN) consist of two classes.
The type I IFN class consists of 20 highly similar IFN-α proteins and a single IFN-ß protein.
The second class, type II IFN, consists of a single protein, IFN-γ.
IFN-α and IFN-ß signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity.
The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts.
IFN-ß has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis.
It is unclear what cellular mechanisms are involved in IFN-ß’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
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