Anti-Mouse CD32/CD16 - Purified in vivo GOLD™ Functional Grade

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609.00 ₪

CD16 is expressed in two forms: CD16a and CD16b.

CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein.

CD16b (FcγRIIIB) is a 48 kD GPI-anchored protein whose extracellular domain is over 95% homologous to that of CD16a.

CD16 regulates both phagocytosis and antibody-dependent cell-mediated cytotoxicity.

It has been reported that CD16 is involved in Natural Killer Cell activation and plays a role in signal transduction.

The receptors, CD32 (FcγRIII) and CD16 (FcγRII), are 40-60 kD and bind antibody-antigen immune complexes and mediate adaptive immune responses.

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Storage and Stability

Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Formulation

This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Shipping Conditions

Next Day 2-8°C