Anti-Mouse CD86 - PE

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640.00 ₪

CD86 is an 80kD Ig superfamily member that is involved in immunoglobulin class-switching and activation of NK cell-mediated cytotoxicity.

CD80 is closely related to, and works in tandem with CD86 to prime T- cells.

CD86 is expressed earlier in the immune response than CD80.

The ligation of CD28 on T cells with CD80 and CD86 on APCs co-stimulates T cells resulting in enhanced cell activation, proliferation, and cytokine production.

CD86 can also bind to CTLA-4 to deliver an inhibitory signal to T cells.

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Storage and Stability

This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.

Formulation

This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

Shipping Conditions

Next Day 2-8°C