Anti-Procollagen Type I C-Peptide (PIP) Antibody (42024)

Price

4,020.00 ₪

Collagens (types I, II, III, IV, and V) are synthesized as precursor molecules called procollagens.

These contain additional peptide sequences, the â€œpropeptidesâ€, at the amino- and carboxy- terminal ends.

Propeptides facilitate the winding of procollagen molecules into a triple-helix conformation within the endoplasmic reticulum.

These propeptides are cleaved from the collagen triple helix during its secretion after which the collagens polymerize into extracellular collagen fibrils.

Therefore, the amount of free propeptides correlates directly with collagen molecule synthesis.

Procollagen Type I C-peptide (PIP) has been extensively referenced in studies that correlated collagen levels and disorders such as bone disease, alcoholic liver disease, liver cirrhosis, and scirrhous (Borrmann type IV) adenocarcinoma of the stomach.

Package Size

Quantity

Storage and Stability

This product does not contain preservative. The stock solution (2. 0mg/ml) can be stored in aliquots at -20°C for 1 year or can be stored at 4°C for 6 months after adding 0.1% sodium azide. Dilutions of stock solution should not be stored.

Formulation

PBS, pH 7.4, 1% BSA, lyophilized.

Shipping Conditions

Next Day 2-8°C