Anti-Sin Nombre Virus (Hantavirus) (Clone: SNV-53)

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1,200.00 ₪

Hantavirus is an enveloped, negative-sensed, single-stranded RNA virus in the bunyavirus family1.

“New World” hantaviruses (NWH) are found in the Americas and may cause hantavirus pulmonary syndrome (HPS)2.

“Old World” hantaviruses (OWH) are found mostly in Europe and Asia and may cause hemorrhagic fever with renal syndrome.

Each hantavirus serotype has a specific rodent host species and infection is spread by aerosolized urine, feces, saliva, or by rodent bites.

Sin Nombre Virus (SNV), a NWH first isolated from rodents in the Southwestern United States, infects with a mortality rate of 50%1.

The probability of survival for Syrian hamsters infected with SNV significantly increases when treated postinfection with the monoclonal antibody (mAb) SNV-533.

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Quantity

Storage and Stability

Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≥ -70°C. Avoid Repeated Freeze Thaw Cycles.

Formulation

This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.

Shipping Conditions

Standard Overnight on Blue Ice.