Bovine Glutamate Dehydrogenase 1, Mitochondrial, GLUD1 ELI

Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate.

Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed: 4365183, PubMed: 14659072).

Plays a role in insulin homeostasis (By similarity).

May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).