Bovine Heparin-binding growth factor 2,FGF2 ELI

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).

Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).

Binds to integrin ITGAV:ITGB3 (By similarity).

Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).

Functions as a potent mitogen in vitro (By similarity).

Can induce angiogenesis (By similarity).

Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).

{ECO:0000250|UniProtKB:P09038}.