Bovine Non-muscle caldesmon,CALD1 ELI

Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments).

Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure.

In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin.

This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin.

Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin.

Also plays an essential role during cellular mitosis and receptor capping.