Chicken Apoptosis regulator Bcl-2,Bcl2 ELI

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells.

Regulates cell death by controlling the mitochondrial membrane permeability.

Appears to function in a feedback loop system with caspases.

Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).