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Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1,PLCG1 EL
Price
3,140.00 ₪
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3).
Plays an important role in the regulation of intracellular signaling cascades.
Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).
Plays a role in actin reorganization and cell migration (PubMed:17229814).
{ECO:0000250|UniProtKB:P10686, ECO:0000269|PubMed:17229814}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
12.59ng/L
Detection range
20-6000ng/L
Shipping Conditions
Next Day Ambient
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