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Human Activin receptor-like kinase 1,ALK1 ELI

Price

‏3,140.00 ‏₪

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development.

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.

Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.

May bind activin as well.

{ECO:0000269|PubMed:22718755, ECO:0000269|PubMed:22799562, ECO:0000269|PubMed:26176610}.

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

0.23ng/ml

Detection range

0.5-150ng/ml

Shipping Conditions

Next Day Ambient
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