Human Alpha-crystallin A Chain, CRYAA ELI

Contributes to the transparency and refractive index of the lens (PubMed: 18302245).

In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions (PubMed: 22120592, PubMed: 31792453).

Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (PubMed: 28935373).