Human Anoctamin 3,ANO3 ELI

Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide (By similarity).

Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (By similarity).

Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:21984732).

{ECO:0000250|UniProtKB:A2AHL1, ECO:0000303|PubMed:21984732}.