Human Apolipoprotein C-2, APOC2 ELI

Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma.

Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.

Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase.

In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.