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Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELI

Price

‏3,140.00 ‏₪

ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane.

Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092).

Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed: 15054092).

The heterodimer with ABCG5 has ATPase activity (PubMed: 16893193, PubMed: 20210363, PubMed: 27144356).

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

12.63ng/L

Detection range

20-7000ng/L

Shipping Conditions

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