Human Atrophin-1, ATN1 ELI

Transcriptional corepressor.

Recruits NR2E1 to repress transcription.

Promotes vascular smooth cell (VSMC) migration and orientation (By similarity).

Corepressor of MTG8 transcriptional repression.

Has some intrinsic repression activity which is independent of the number of poly-Gln (polyQ) repeats.