Human Bcl2 Antagonist of Cell Death, BAD ELI

Promotes cell death.

Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX.

Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity).

Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.