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Human Bone Morphogenetic Protein 2, BMP-2 ELI

Price

‏3,140.00 ‏₪

Induces cartilage and bone formation (PubMed: 3201241).

Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway.

BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation.

In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed: 24362451).

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

0.01ng/ml

Detection range

0.05-15ng/ml

Shipping Conditions

Next Day Ambient
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