Human Bone Morphogenetic Protein 2, BMP2 Primacu™ ELI

BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage.

BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types.

BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair.

In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.