Human C-type Lectin Domain Family 4 Member C, CLEC4C ELI
3,140.00 ₪
Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed: 11748283, PubMed: 21880719, PubMed: 25995448).
Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed: 21880719, PubMed: 25995448).
Binds to serum IgG (PubMed: 25995448).
Efficiently targets ligand into antigen-processing and Peptide-loading compartments for presentation to T-cells (PubMed: 11748283).
May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PubMed: 11748283, PubMed: 21880719).
May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed: 11748283).
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