Human C-type Lectin Domain Family 7 Member A, CLEC7A ELI

Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi.

Induces phosphorylation of SCIMP after binding beta-glucans (By similarity).

Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B.

Enhances cytokine production in macrophages and dendritic cells.

Mediates production of reactive oxygen species in the cell.

Mediates phagocytosis of C.albicans conidia.

Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation.

Stimulates T-cell proliferation (By similarity).