Human Calcium Calmodulin-dependent Protein Kinase Type 1D, CAMK1D ELI

Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons.

In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst.

Activates the transcription factor CREB1 in hippocampal neuron nuclei.

May play a role in apoptosis of erythroleukemia cells.

In vitro, phosphorylates transcription factor CREM isoform Beta.