Human Carbohydrate Sulfotransferase 9, CHST9 ELI

Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans.

Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures.

Has a higher activity toward carbonic anhydrase VI than toward lutropin.

Only active against terminal GalNAcbeta1,GalNAcbeta.

Isoform 2, but not isoform 1, is active toward chondroitin.