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Human Carbonyl Reductase Nadph 1, CBR1 ELI

Price

‏3,140.00 ‏₪

NADPH-dependent reductase with broad substrate specificity.

Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics.

Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol (PubMed:18449627, PubMed:15799708, PubMed:17912391, PubMed:7005231). Can convert prostaglandin E to prostaglandin F2-alpha (By similarity). Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.

Catalyzes the reduction of S-nitrosoglutathione (PubMed:18826943, PubMed:17344335).

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

9.31ng/L

Detection range

20-4500ng/L

Shipping Conditions

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