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Human Caspase 10,CASP10 ELI
Price
3,140.00 ₪
Involved in the activation cascade of caspases responsible for apoptosis execution.
Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner.
May participate in the granzyme B apoptotic pathways.
Cleaves and activates caspase-3, -4, -6, -7, -8, and -9.
Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
{ECO:0000269|PubMed:11717445}.; Isoform 7 can enhance NF-kappaB activity but promotes only slight apoptosis.
{ECO:0000269|PubMed:17822854}.; Isoform C is proteolytically inactive.
{ECO:0000269|PubMed:11717445}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
0.21ng/ml
Detection range
0.38-24ng/ml
Shipping Conditions
Next Day Ambient
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