Human Caspase 2,CASP2 ELI

Involved in the activation cascade of caspases responsible for apoptosis execution.

Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival (PubMed:15073321).

Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress (PubMed:15073321).

{ECO:0000269|PubMed:15073321}.