Human Catenin Alpha 2, CTNNA2 ELI

May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (By similarity).

Required for proper regulation of cortical neuronal migration and neurite growth (PubMed: 30013181).

It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization (PubMed: 30013181).

It thereby suppresses excessive actin branching which would impair neurite growth and stability (PubMed: 30013181).

Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development.

Functions in the control of startle modulation (By similarity).