Human Cathepsin B, CATH-B ELI

Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed: 12220505).

Cleaves matrix extracellular phosphoglycoprotein MEPE (PubMed: 12220505).

Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity).

Has also been implicated in tumor invasion and metastasis (PubMed: 3972105).