Human Caveolin 2, CAV2 ELI

May act as a scaffolding protein within caveolar membranes.

Interacts directly with G-protein alpha subunits and can functionally regulate their activity.

Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.

The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.

Positive regulator of cellular mitogenesis of the MAPK signaling pathway.

Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).