Human Class A basic helix-loop-helix protein 15,bHLHa15 ELI

Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated.

Repression may occur through muscle-specific E-box occupancy by homodimers.

May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain.

Serves as a key regulator of acinar cell function, stability, and identity.

Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport.

May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages.

Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).

{ECO:0000250|UniProtKB:Q9QYC3}.