Human Complement C1Q-like Protein 3, C1QL3 ELI

May regulate the number of excitatory synapses that are formed on hippocampus neurons.

Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis.

Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake.

In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production (By similarity).