Human Complement Component C7, C7 Primacu™ ELI
3,970.00 ₪
Complement component 7 is a component of the complement system.
It belongs to the complement C6/C7/C8/C9 family.
It contains 1 EGF-like domain, 1 LDL-receptor class A domain, 1 MACPF domain, 2 Sushi (CCP/SCR) domains and 2 TSP type-1 domains.
Complement component 7 serves as a membrane anchor.
It participates in the formation of Membrane Attack Complex (MAC).
People with C7 deficiency are prone to bacterial infection.
It is a constituent of MAC that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Defects in C7 are a cause of complement component 7 deficiency (C7D).
A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
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