Human CXC-chemokine ligand 17,CXCL17 ELI
3,140.00 ₪
Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells (PubMed:16455961, PubMed:23115081).
Plays a role in angiogenesis and possibly in the development of tumors (PubMed:16989774, PubMed:23115081).
Acts as an anti-inflammatory in the stomach (PubMed:23115081).
May play a role in the innate defense against infections (PubMed:17307946).
Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions (PubMed:25411203).
{ECO:0000269|PubMed:16455961, ECO:0000269|PubMed:16989774, ECO:0000269|PubMed:17307946, ECO:0000269|PubMed:23115081, ECO:0000269|PubMed:25411203}.; [4-Cys CXCL17]: seems exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17.
{ECO:0000269|PubMed:23115081}.
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