Human Cytokine-like Protein 1, CYTL1 ELI

Cytokine-like 1 (CYTL1) is a protein that in humans is encoded by the CYTL1 gene.

C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 surface marker.

Functionally, C17 was identified as a secretory protein expressed in CD34+ haemopoietic cells.

CYTL1 seems to regulate chondrogenesis and is required for the maintenance of cartilage homeostasis and might, additionally, work as a regulatory factor in embryo implantation in the stage of early pregnancy.

This family of proteins, C17, is found in vertebrates.

Proteins have two conserved sequence motifs: PPTCYSR and DDC.