Human Cytosolic Carboxypetidase 3, CCP3 ELI

Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins.

Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins.

Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK.

Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.

[Isoform 2]: Metallocarboxypeptidase that mediates tubulin deglutamylation.