Human Deiodinase Iodothyronine Type 1,DIO1 ELI

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.