Human Dipeptidase 2, DPEP2 ELI

Dipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).

Does not hydrolyze cystinyl-bis-glycine.

Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF-kappaB inflammatory signaling pathway.