Human Disintegrin and metalloproteinase domain-containing protein 2,ADAM2 ELI

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization.

Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct.

Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg.

This is a non catalytic metalloprotease-like protein.