Human Drebrin, DBN1 ELI

Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed: 20215400).

Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMed: 20215400).

Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity).

Involved in memory-related synaptic plasticity in the hippocampus (By similarity).