Human Dynactin Subunit 5, DCTN5 ELI

Dynactin 5 (p25) is a protein that in humans is encoded by the DCTN5 gene.

This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport.

The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo.

A pseudogene of this gene is located on the long arm of chromosome 1.

Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.