Human Dystrophin, DMD ELI

Anchors the extracellular matrix to the cytoskeleton via F-actin.

Ligand for dystroglycan.

Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma.

Also implicated in signaling events and synaptic transmission.