Human Eosinophil-associated, ribonuclease A family, member 3,EAR3 ELI

Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity.

Possesses a wide variety of biological activities.

Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains.

Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

{ECO:0000269|PubMed:19450231, ECO:0000269|PubMed:2501794}.