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Human Erlin-2, ERLIN2 ELI

Price

‏3,140.00 ‏₪

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed: 19240031, PubMed: 17502376).

Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed: 21343306).

Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.

May promote ER retention of the SCAP-SREBF complex (PubMed: 24217618).

Package Size

Quantity

Storage and Stability

2-8ºC

Sensitivity

5.15ng/L

Detection range

10-2000ng/L

Shipping Conditions

Next Day Ambient
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