Human Estradiol 17-beta-dehydrogenase 11,HSD17B11 ELI

Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis.

May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it.

Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.

Tumor-associated antigen in cutaneous T-cell lymphoma.