Human Eukaryotic Elongation Factor 2 Kinase, EEF2K ELI

Threonine kinase that regulates protein synthesis by controlling the rate of Peptide chain elongation.

Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive.

In turn, the rate of protein synthesis is reduced.