Human Filamin-C, FLNC ELI

Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein.

May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells.

Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.