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Human Gephyrin,GPHN ELI
Price
3,140.00 ₪
Microtubule-associated protein involved in membrane protein-cytoskeleton interactions.
It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity).
Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors (PubMed:25025157, PubMed:26613940).
{ECO:0000250|UniProtKB:Q03555, ECO:0000269|PubMed:25025157, ECO:0000269|PubMed:26613940}.; Has also a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor.
In the first step, molybdopterin is adenylated.
Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
{ECO:0000269|PubMed:26613940}.
Quantity
Storage and Stability
2-8ºC
Sensitivity
42.55pg/ml
Detection range
100-6400pg/ml
Shipping Conditions
Next Day Ambient
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