Human Gonadotropin-releasing Hormone Receptor, GNRHR ELI

Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

Isoform 2 may act as an inhibitor of GnRH-R signaling.