Human High sensitivity C-C motif chemokine 2,CCL2 ELI
3,140.00 ₪
Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:9837883, PubMed:10587439, PubMed:10529171).
Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:9837883, PubMed:10587439).
Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8627182, PubMed:9792674, PubMed:8195247).
May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690).
{ECO:0000269|PubMed:10529171, ECO:0000269|PubMed:10587439, ECO:0000269|PubMed:8107690, ECO:0000269|PubMed:8195247, ECO:0000269|PubMed:8627182, ECO:0000269|PubMed:9792674, ECO:0000269|PubMed:9837883}.
Quantity