Human Inactive Phospholipase C-like Protein 1, PLCL1 ELI

Involved in an inositol phospholipid-based intracellular signaling cascade.

Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.

Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition.

Its aberrant expression could contribute to the genesis and progression of lung carcinoma.

Acts as an inhibitor of PPP1C.